APOCYNIN, A SELECTIVE NADPH OXIDASE (NOX2) INHIBITOR, AMELIORATES BEHAVIOURAL AND LEARNING DEFICITS IN THE FRAGILE X SYNDROME MOUSE MODEL

Apocynin, a Selective NADPH Oxidase (Nox2) Inhibitor, Ameliorates Behavioural and Learning Deficits in the Fragile X Syndrome Mouse Model

Background/Objectives: Fragile X Syndrome (FXS) is associated with intellectual disability, hyperactivity, social anxiety and signs of autism.Hyperactivation of NADPH oxidase has been previously described in the brain of the male Porridge Fmr1-KO mouse.This work aims to demonstrate the efficacy of Apocynin, a specific NADPH oxidase inhibitor, in tr

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Difficult weaning in delayed onset diaphragmatic hernia

Diaphragmatic injuries are relatively rare and result from either blunt or penetrating trauma.Regardless of the mechanism, diagnosis is often missed and high index of suspicion is vital.The clinical signs associated with a diaphragmatic hernia can range from Kites no outward signs to immediately life-threatening respiratory compromise.Establishing

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COVID-19 Prognosis in Children With Asthma

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new coronavirus disease that is highly contagious and affects all age groups of children.The incubation period of Coronavirus disease Face toner mist (COVID-19) ranges from 2 to 14 days.Diagnosis of COVID-19 is made by conducting nasal and pharyngeal swabs and analyzing sputum, stool

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